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Half life pharmacology definition

half life pharmacology definition

The basis of this decontamination method (used at Harwell ) citation needed is geography of time pdf to increase the rate at which the water in the body is replaced with new water.
Grapefruit and grapefruit juice can cause problems with this, and the clinician may tell one to avoid this food.Also the rate-limiting steps for one substance may be in common with other substances.When being treated for blood pressure problems (Hypertension) or cholesterol problems (Hyperlipidemia) you'd like the medication to work all day.A drug media player classic terbaru november 2013 molecule that leaves the plasma may have any of several fates: it can be destroyed in the blood; it can be eliminated from the body; or it can be translocated to a body fluid compartment other than the intravascular to be stored, biotransformed.Also, when a medication has to be stopped, it is often desirable to reduce it over time, instead of stopping it all at once."Pharmacokinetics of oxaliplatin in humans".Archived from the original.10 11 Lead in bone has a biological half-life of about ten years.Cadmium in bone has a biological half-life of about 30 years.When the plot of log plasma or serum game mobil balap formula 1 concentration (during the period of its decline) against time is composed of two straight line segments, the inference may be made that two first order processes are involved in the distribution and biotransformation and elimination of the.
The prussian blue in the digestive system acts as a solid ion exchanger which absorbs the caesium while releasing potassium ions.

Sample values and equations edit Characteristic Description Example value Symbol Formula Dose Amount of drug administered.Intravenous) peptides like oxytocin cross the blood-brain-barrier very poorly, although very small amounts ( 1) do appear to enter the central nervous system in humans when given via this route.Plutonium in the liver has a biological half-life of about 40 years."Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration".New York: McGraw-Hill Medical.The given concentration or amount need not be the maximum observed during the course of the experiment, or the concentration or amount present at the beginning of an experiment, since the half-life is completely independent of the concentration or amount chosen as the starting point.
This value is constant in first-order kinetics, and independent of drug concentration.
Handbook on the toxicology of metals.